The BioGenix regenerative medicine product contains primitive undifferentiated stem cells and additional growth factors which are beneficial for repair , growth and healing . BioGenix has independently completed in vitro studies that illustrate the quantity of cells and cell surface markers indicative of stem cells obtained from our BioGenix regenerative medicine product . Most importantly, the release of growth factors that aid in the formation of new blood vessels, activation of endogenous stem cells, modulation of the immune system and growth of cells and tissue . The stem cells we are using are harvested from cord blood and tissue that has been isolated in a sterile environment and rigorously tested . The product is positive for MSC's marker CD90 .
Most importantly, the BioGenix regenerative medicine product contains growth factors and cytokines such as vascular endothelial cell growth factor ( VEGF ) that helps restore oxygenation to tissues and cells when blood supply is inadequate , stem cell factor (SCF) to mediate cell survival, migration and proliferation depending on the cell type . SCF plays a crucial role of such things as hematopoiesis, pigmentation, gut movement, and some aspects of the nervous system. The fibroblast growth factor (FGF - 2) is essential for growth and development of bone and cartilage formation and interleukin 1 receptor antagonist (IL - 1ra) is responsible for controlling the inflammatory response that occurs in many disease and trauma states . Many more growth factors are included .
The BioGenix lab research doctors also the inventors of a cutting edge patent pending DNA modification technology which is published in medical works and USPTO . BioGenix is a fully sterile lab and uses only sell non expanded and non contaminated cells . All stem cells that come out of the BioGenix lab are internally verified and third party before release to doctors . Certification is shipped with the cells .
At the time of birth , a specialized nurse enters the delivery room to carry out the extraction procedures . Our product, voluntarily donated human umbilical cord of healthy full term babies was harvested and processed into the BioGenix products in sterile, FDA - compliant and AABT - compliant laboratory . We only harvest stem cells from California hospitals . We never, ever purchase cord blood from foreign countries in bulk , as many of our competitors do. BioGenix finds this type of practice repulsive . Our professional relationship with our local California hospitals is paramount. With the mothers informed consent, the umbilical cord is clamped off when the baby is born . This preserves the blood in the cord . Besides the blood in the cord , within the umbilical cord is a gelatinous substance, Wharton's jelly. Cells in Wharton's jelly express several stem cell genes , including telomerase. Wharton's jelly is therefore a potential source of adult stem cells . Wharton's jelly - derived mesenchymal stem cells may have immunomodulatory effect on lymphocytes . As a mucous tissue, it protects and insulates the umbilical blood vessels . Hence, the umbilical cord content we utilize contains the cord blood & Wharton's jelly, referred to as tissue . Many companies only utilize cord blood . Our distinction of an umbilical cord derived product containing both cord blood and Wharton's Jelly is superior to most other cord blood companies .
Donor eligibility is carefully assessed in accordance with AATB standards as required by the FDA . A donors medical history and social history is reviewed and an interview is performed in accordance with FDA CFR 21 , 1271 (n) . Tissue from donors who engaged in high risk behaviors and relevant communicable diseases are excluded . Screening also includes a physical health assessment, serology for evidence of relevant communicable diseases or incompatibility to blood markers, and microbiological screening of the collected tissues. An FDA - registered laboratory use FDA - approved test kits to perform the indicated tests, in compliance with the Clinical Laboratory Improvement Amendments of 1988 (CLIA) and the required laboratory requirements described in 42 CFR Part 493 .
Most labs in the United States buy from tissue banks that resale expanded cells . Our stem cells are not expanded . They are pure non-expanded cells . BioGenix products are cryopreserved in a proprietary solution without DMSO and stored at -80 C or below . BioGenix harvests the cells from the blood and Wharton Jelly from each individual umbilical cord in a FDA - compliant laboratory in accordance with Current Good Manufacturing Practices (CGMP) , Current Good Tissue Practice (CGTP) and additional requirements for sterile allograft products processed in compliance with American Association of Tissue Banks (AATB) regulations .
The federal government has chosen BioGenix as the only authorized stem cell company to exclusively provide stem cell therapy to every Veterans Administration ( VA ) Hospital in the United States . This vetting process was extensive and took many months to complete . Our exclusive contract with the United States government is a source of pride as we continue to improve the health of our heroic veterans .
BioGenix regenerative medicine product is one of the most unique stem cell / regenerative medicine products that exists today . Our product contains many factors that , in host , repair and heal various trauma and disease states, falls into the ISCT criteria of MSC's and also contains growth factors that play a role in angiogenesis, growth and repair of cartilage and bone tissue, which should serve well in orthopedic disease , and a wide array of autoimmune diseases .
Umbilical cord mesenchymal stem cells will proliferate quicker than MSC's from adipose tissue or bone marrow . They form significantly more bone nodules in vitro than MSC's from adipose tissue or bone marrow . UC MSC's differentiate into significantly fewer adipocytes ( fat cells ) than MSC's from adipose tissue . UC MSC's has lower expression of HLA - DMA , HLA - DPB1 , HLA - DRA than other sources of MSC's . Bone marrow MSC's had the highest expression . UC MSC's shows the highest inhibition of T cell proliferation of four MSC's sources .